Built by the bold, backed by Revolution

Tempus was founded with a bold goal: bring AI to clinical care at scale. After dealing with the limitations of the existing system during his wife’s battle with breast cancer, serial entrepreneur Eric Lefkofsky began building the team, platform, and partnerships to amass one of the largest libraries of clinical and genomic data in the world and make precision medicine a reality for more people.

We were confident in the market opportunity (healthcare, after all, is one of the largest and most ripe-for-disruption sectors) and drawn to Tempus’s mission to make sure each patient receives the right treatment to live a longer and healthier life. We were also confident that Eric and his team had the track record and technical depth to turn that mission into a platform physicians, hospitals, and pharmaceutical companies could trust. From Series C to IPO, we supported the company’s progress with key introductions and board development as it grew from 50 employees to thousands, expanded into new disease areas, and proved what a virtuous cycle of research, data, and machine learning could achieve in healthcare.

‍

Navigating an M&A deal is complex—and post-close administration often creates even more friction for shareholders, buyers, and legal teams. SRS Acquiom was founded to simplify that process. Combining experienced deal professionals with purpose-built technology, the company set out to streamline shareholder representation, payments, and escrow services—making post-transaction workflows faster, more secure, and more transparent.

We saw a clear opportunity to modernize a critical but underserved part of the private market. SRS Acquiom brought unique insight into the M&A lifecycle and created a trusted position at the center of thousands of deals. We backed the company early to help scale that vision and enable the company to enter the asset management business for merger escrows. To date, the team has facilitated 10K+ M&A transactions valued at $1.7T+, and represented 560K+ shareholders across 140+ countries.

The sneaker resale world was booming, but messy. Prices were inconsistent, trust was low, and fakes were everywhere. StockX set out to systematize the exchange by creating the first “stock market of things,” where buyers and sellers could transact with real-time pricing, guaranteed authenticity, and a marketplace built on data, not guesswork. And they did it from Detroit, turning a local idea into a global platform.

We saw a booming market with no clear infrastructure and a platform with the potential to bring order to the chaos. Founded and backed by Dan Gilbert—whose commitment to investing in Detroit has been a catalytic force in the city’s resurgence—StockX set out to build a global consumer marketplace, and build it in Detroit. We backed the team early as they reimagined what the current culture economy could be: credible, efficient, and built for scale.

Residential real estate was one of the last major industries to go mobile, which left agents working with outdated, fragmented tools. Homesnap set out to modernize the experience with a platform designed around how agents actually operate: on the move, in the field, and in constant communication with clients. By integrating real-time MLS data with intuitive mobile workflows, the team aimed to bring new speed, clarity, and trust to the home-buying process.

We saw in Homesnap an opening to modernize a critical part of the housing market by meeting agents where they are. The team built with a deep understanding of the on-the-go workflow, earning trust across MLSs and becoming an essential platform in a historically slow-to-adopt industry. As traction grew, we supported the team through key growth milestones, helping build out the leadership team with CEO John Mazur and ultimately facilitating its 2020 acquisition by CoStar as part of its push into residential real estate.

CAVA’s co-founders set out to share the flavors and traditions of their Mediterranean heritage with consumers, and to do it at scale without sacrificing authenticity or hospitality. The team reimagined fast casual dining by pairing bold, healthy food with a tech-enabled customer experience that made high-quality meals more accessible.

‍

CAVA had all the right ingredients: a clear mission, a craveable product, and disciplined leadership. The team was eager to embrace technology and meet more people in more places with food that fuels and connects, and we were eager to help them get to scale.

With early board involvement and growth capital, we supported CAVA as it expanded nationally—from integrating technology across operations to strengthening brand, governance, and go-to-market strategy.

With a defense industry dominated by legacy contractors and sluggish procurement cycles, Anduril set out to take a different approach—one that moved at the speed of software. Founded by a team of experienced tech entrepreneurs and operators, the company aimed to rebuild the defense stack from the ground up, using AI, autonomous systems, and real-time data to equip the U.S. and its allies with modern tools for a new era of national security.

Anduril is building what America needs: a fast, flexible defense industrial base rooted in cutting-edge technology and domestic manufacturing. By deploying functional systems early and iterating with operators in the field, they’re proving that incumbents don’t have a monopoly on innovation, even in highly regulated industries. We backed them early because the mission was urgent—and the model, overdue.

‍